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Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients

This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10–20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10–20 mcg/mL, while 44 patients (79%) obtained trough lev...

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Detalles Bibliográficos
Autores principales: Orr, Hillary, Trone, Deni, Elder, Joshua, Raj, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615269/
https://www.ncbi.nlm.nih.gov/pubmed/28846665
http://dx.doi.org/10.3390/children4090079
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author Orr, Hillary
Trone, Deni
Elder, Joshua
Raj, Ashok
author_facet Orr, Hillary
Trone, Deni
Elder, Joshua
Raj, Ashok
author_sort Orr, Hillary
collection PubMed
description This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10–20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10–20 mcg/mL, while 44 patients (79%) obtained trough levels below 10 mcg/mL despite the addition of nephrotoxic agents.
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spelling pubmed-56152692017-09-28 Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients Orr, Hillary Trone, Deni Elder, Joshua Raj, Ashok Children (Basel) Brief Report This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10–20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10–20 mcg/mL, while 44 patients (79%) obtained trough levels below 10 mcg/mL despite the addition of nephrotoxic agents. MDPI 2017-08-28 /pmc/articles/PMC5615269/ /pubmed/28846665 http://dx.doi.org/10.3390/children4090079 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Orr, Hillary
Trone, Deni
Elder, Joshua
Raj, Ashok
Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients
title Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients
title_full Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients
title_fullStr Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients
title_full_unstemmed Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients
title_short Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients
title_sort assessment of initial vancomycin dosing in pediatric oncology patients
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615269/
https://www.ncbi.nlm.nih.gov/pubmed/28846665
http://dx.doi.org/10.3390/children4090079
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