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Reduced Cytokine Release in Ex Vivo Response to Cilengitide and Cetuximab Is a Marker for Improved Survival of Head and Neck Cancer Patients
Targeting of α(V)β3 and α(V)β5 integrins by cilengitide may reduce growth of solid tumors including head and neck squamous cell carcinoma (HNSCC). Preclinical investigations suggest increased activity of cilengitide in combination with other treatment modalities. The only published trial in HNSCC (A...
Autores principales: | Cedra, Susan, Wiegand, Susanne, Kolb, Marlen, Dietz, Andreas, Wichmann, Gunnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615332/ https://www.ncbi.nlm.nih.gov/pubmed/28872582 http://dx.doi.org/10.3390/cancers9090117 |
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