EML4-ALK Variants: Biological and Molecular Properties, and the Implications for Patients

Since the discovery of the fusion between EML4 (echinoderm microtubule associated protein-like 4) and ALK (anaplastic lymphoma kinase), EML4-ALK, in lung adenocarcinomas in 2007, and the subsequent identification of at least 15 different variants in lung cancers, there has been a revolution in molec...

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Detalles Bibliográficos
Autores principales: Sabir, Sarah R., Yeoh, Sharon, Jackson, George, Bayliss, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615333/
https://www.ncbi.nlm.nih.gov/pubmed/28872581
http://dx.doi.org/10.3390/cancers9090118

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