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The PI3Kδ Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL

The quest continues for targeted therapies to reduce the morbidity of chemotherapy and to improve the response of resistant leukemia. Adhesion of acute lymphoblastic leukemia (ALL) cells to bone marrow stromal cells triggers intracellular signals that promote cell-adhesion-mediated drug resistance (...

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Detalles Bibliográficos
Autores principales:	Adam, Etai, Kim, Hye Na, Gang, Eun Ji, Schnair, Caitlin, Lee, Solomon, Lee, Solah, Khazal, Sajad, Kosoyan, Osanna, Konopleva, Marina, Parekh, Chintan, Bhojwani, Deepa, Wayne, Alan S., Abdel-Azim, Hisham, Heisterkamp, Nora, Kim, Yong-Mi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615336/ https://www.ncbi.nlm.nih.gov/pubmed/28891959 http://dx.doi.org/10.3390/cancers9090121

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