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RECQ1 Helicase Silencing Decreases the Tumour Growth Rate of U87 Glioblastoma Cell Xenografts in Zebrafish Embryos

RECQ1 helicase has multiple roles in DNA replication, including restoration of the replication fork and DNA repair, and plays an important role in tumour progression. Its expression is highly elevated in glioblastoma as compared to healthy brain tissue. We studied the effects of small hairpin RNA (s...

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Detalles Bibliográficos
Autores principales: Vittori, Miloš, Breznik, Barbara, Hrovat, Katja, Kenig, Saša, Lah, Tamara T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615355/
https://www.ncbi.nlm.nih.gov/pubmed/28878163
http://dx.doi.org/10.3390/genes8090222