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Development of an antibiotic marker-free platform for heterologous protein production in Streptomyces
BACKGROUND: The industrial use of enzymes produced by microorganisms is continuously growing due to the need for sustainable solutions. Nevertheless, many of the plasmids used for recombinant production of proteins in bacteria are based on the use of antibiotic resistance genes as selection markers....
Autores principales: | Sevillano, Laura, Díaz, Margarita, Santamaría, Ramón I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615484/ https://www.ncbi.nlm.nih.gov/pubmed/28950904 http://dx.doi.org/10.1186/s12934-017-0781-y |
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