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Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China

Despite risks associated with perfluoroalkyl acids (PFAAs) in many regions, little is known about their prevalence in Xinjiang. We determined the presence of 13 PFAAs in 293 beef muscle and liver samples collected in 22 cities covering northern, southern, and eastern Xinjiang using liquid chromatogr...

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Autores principales: Wang, Gehui, Lu, Jianjiang, Xing, Zhenni, Li, Shanman, Liu, Zilong, Tong, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615507/
https://www.ncbi.nlm.nih.gov/pubmed/28846636
http://dx.doi.org/10.3390/ijerph14090970
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author Wang, Gehui
Lu, Jianjiang
Xing, Zhenni
Li, Shanman
Liu, Zilong
Tong, Yanbin
author_facet Wang, Gehui
Lu, Jianjiang
Xing, Zhenni
Li, Shanman
Liu, Zilong
Tong, Yanbin
author_sort Wang, Gehui
collection PubMed
description Despite risks associated with perfluoroalkyl acids (PFAAs) in many regions, little is known about their prevalence in Xinjiang. We determined the presence of 13 PFAAs in 293 beef muscle and liver samples collected in 22 cities covering northern, southern, and eastern Xinjiang using liquid chromatography, coupled with tandem mass spectrometry. Overall, the average values for PFAAs were relatively low compared with previous studies. Liver presented higher mean levels of total PFAAs at 1.632 ng/g, which was over 60-fold higher than in muscle (0.026 ng/g). Among the PFAAs analyzed, medium-chain compounds were dominant, accounting for more than 70% of the total. Perfluorooctane sulfonate (PFOS) was highly prevalent in the liver with the highest mean concentration (0.617 ng/g) and detection frequency (80%). When comparing the three regions of Xinjiang, we found differences in PFAA profiles, with the northern region showing the highest levels. Furthermore, the average daily intake and hazard ratios of PFOS and perfluorooctanoic acid varied by region, urban/rural environment, gender, ethnicity, and age. The highest risk value of 13 PFAAs was estimated to be 0.837 × 10(−3), which is far below 1, indicating that there is no health risk posed by eating beef muscle and liver in Xinjiang.
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spelling pubmed-56155072017-09-30 Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China Wang, Gehui Lu, Jianjiang Xing, Zhenni Li, Shanman Liu, Zilong Tong, Yanbin Int J Environ Res Public Health Article Despite risks associated with perfluoroalkyl acids (PFAAs) in many regions, little is known about their prevalence in Xinjiang. We determined the presence of 13 PFAAs in 293 beef muscle and liver samples collected in 22 cities covering northern, southern, and eastern Xinjiang using liquid chromatography, coupled with tandem mass spectrometry. Overall, the average values for PFAAs were relatively low compared with previous studies. Liver presented higher mean levels of total PFAAs at 1.632 ng/g, which was over 60-fold higher than in muscle (0.026 ng/g). Among the PFAAs analyzed, medium-chain compounds were dominant, accounting for more than 70% of the total. Perfluorooctane sulfonate (PFOS) was highly prevalent in the liver with the highest mean concentration (0.617 ng/g) and detection frequency (80%). When comparing the three regions of Xinjiang, we found differences in PFAA profiles, with the northern region showing the highest levels. Furthermore, the average daily intake and hazard ratios of PFOS and perfluorooctanoic acid varied by region, urban/rural environment, gender, ethnicity, and age. The highest risk value of 13 PFAAs was estimated to be 0.837 × 10(−3), which is far below 1, indicating that there is no health risk posed by eating beef muscle and liver in Xinjiang. MDPI 2017-08-28 2017-09 /pmc/articles/PMC5615507/ /pubmed/28846636 http://dx.doi.org/10.3390/ijerph14090970 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Gehui
Lu, Jianjiang
Xing, Zhenni
Li, Shanman
Liu, Zilong
Tong, Yanbin
Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
title Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
title_full Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
title_fullStr Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
title_full_unstemmed Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
title_short Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
title_sort occurrence, distribution, and risk assessment of perfluoroalkyl acids (pfaas) in muscle and liver of cattle in xinjiang, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615507/
https://www.ncbi.nlm.nih.gov/pubmed/28846636
http://dx.doi.org/10.3390/ijerph14090970
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