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AMP-activated protein kinase – not just an energy sensor
Orthologues of AMP-activated protein kinase (AMPK) occur in essentially all eukaryotes as heterotrimeric complexes comprising catalytic α subunits and regulatory β and γ subunits. The canonical role of AMPK is as an energy sensor, monitoring levels of the nucleotides AMP, ADP, and ATP that bind comp...
Autores principales: | Hardie, David Grahame, Lin, Sheng-Cai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615778/ https://www.ncbi.nlm.nih.gov/pubmed/29034085 http://dx.doi.org/10.12688/f1000research.11960.1 |
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