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Sulfur mustard-stimulated proteases and their inhibitors in a cultured normal human epidermal keratinocytes model: A potential approach for anti-vesicant drug development

Protease stimulation in cultured normal human epidermal keratinocytes (NHEK) due to sulfur mustard (SM) exposure is well documented. However, the specific protease(s) stimulated by SM and the protease substrates remain to be determined. In this study, we observed that SM stimulates several proteases...

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Detalles Bibliográficos
Autores principales: Jin, Xiannu, Ray, Radharaman, Ray, Prabhati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615839/
https://www.ncbi.nlm.nih.gov/pubmed/28959561
http://dx.doi.org/10.1016/j.toxrep.2016.03.007