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Activation of phosphoinositide 3-kinase/Akt/mechanistic target of rapamycin pathway and response to everolimus in endocrine receptor-positive metastatic breast cancer – A retrospective pilot analysis and viewpoint

INTRODUCTION: Biomarkers predictive of response to mechanistic target of rapamycin (mTOR) inhibitor, everolimus, in endocrine receptor (ER)-positive metastatic breast cancer (MBC) are a work in progress. We evaluated the feasibility of directly measuring mTOR activity and phosphatase and tensin homo...

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Detalles Bibliográficos
Autores principales:	Bajpai, Jyoti, Ramaswamy, Anant, Chandrasekharan, Arun, Mishra, Surya, Shet, Tanuja, Gupta, Sudeep, Badwe, R. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2017
Materias:	ORIGINAL ARTICLE: Breast Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615875/ https://www.ncbi.nlm.nih.gov/pubmed/28975114 http://dx.doi.org/10.4103/sajc.sajc_113_17

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