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It's easier to get along with the quiet neighbours
Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, 2017) suggests this is the exception not the rule. Rather i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615921/ https://www.ncbi.nlm.nih.gov/pubmed/28951503 http://dx.doi.org/10.15252/msb.20177961 |
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author | Hurst, Laurence D |
author_facet | Hurst, Laurence D |
author_sort | Hurst, Laurence D |
collection | PubMed |
description | Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, 2017) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise. |
format | Online Article Text |
id | pubmed-5615921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56159212017-09-28 It's easier to get along with the quiet neighbours Hurst, Laurence D Mol Syst Biol News & Views Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, 2017) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise. John Wiley and Sons Inc. 2017-09-26 /pmc/articles/PMC5615921/ /pubmed/28951503 http://dx.doi.org/10.15252/msb.20177961 Text en © 2017 The Author. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the Creative Commons Attribution 4.0 (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | News & Views Hurst, Laurence D It's easier to get along with the quiet neighbours |
title | It's easier to get along with the quiet neighbours |
title_full | It's easier to get along with the quiet neighbours |
title_fullStr | It's easier to get along with the quiet neighbours |
title_full_unstemmed | It's easier to get along with the quiet neighbours |
title_short | It's easier to get along with the quiet neighbours |
title_sort | it's easier to get along with the quiet neighbours |
topic | News & Views |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615921/ https://www.ncbi.nlm.nih.gov/pubmed/28951503 http://dx.doi.org/10.15252/msb.20177961 |
work_keys_str_mv | AT hurstlaurenced itseasiertogetalongwiththequietneighbours |