Cargando…

It's easier to get along with the quiet neighbours

Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, 2017) suggests this is the exception not the rule. Rather i...

Descripción completa

Detalles Bibliográficos
Autor principal: Hurst, Laurence D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615921/
https://www.ncbi.nlm.nih.gov/pubmed/28951503
http://dx.doi.org/10.15252/msb.20177961
_version_ 1783266690826502144
author Hurst, Laurence D
author_facet Hurst, Laurence D
author_sort Hurst, Laurence D
collection PubMed
description Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, 2017) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise.
format Online
Article
Text
id pubmed-5615921
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-56159212017-09-28 It's easier to get along with the quiet neighbours Hurst, Laurence D Mol Syst Biol News & Views Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al, 2017) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise. John Wiley and Sons Inc. 2017-09-26 /pmc/articles/PMC5615921/ /pubmed/28951503 http://dx.doi.org/10.15252/msb.20177961 Text en © 2017 The Author. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the Creative Commons Attribution 4.0 (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News & Views
Hurst, Laurence D
It's easier to get along with the quiet neighbours
title It's easier to get along with the quiet neighbours
title_full It's easier to get along with the quiet neighbours
title_fullStr It's easier to get along with the quiet neighbours
title_full_unstemmed It's easier to get along with the quiet neighbours
title_short It's easier to get along with the quiet neighbours
title_sort it's easier to get along with the quiet neighbours
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615921/
https://www.ncbi.nlm.nih.gov/pubmed/28951503
http://dx.doi.org/10.15252/msb.20177961
work_keys_str_mv AT hurstlaurenced itseasiertogetalongwiththequietneighbours