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GLP-1 receptor agonist exenatide restores atypical antipsychotic clozapine treatment-associated glucose dysregulation and damage of pancreatic islet beta cells in mice

BACKGROUND AND AIMS: The aim of this study was to investigate the effect of a glucagon-like peptide-1 receptor agonist (GLP-1RA), exenatide, on clozapine-associated glucose dysregulation in mice. MATERIALS AND METHODS: We randomly separated B6 male mice into four groups (A to D). Mice in groups C an...

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Detalles Bibliográficos
Autores principales: Hsu, Brend Ray-Sea, Fu, Shin-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615926/
https://www.ncbi.nlm.nih.gov/pubmed/28959568
http://dx.doi.org/10.1016/j.toxrep.2016.04.005