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Polydatin Prevents Methylglyoxal-Induced Apoptosis through Reducing Oxidative Stress and Improving Mitochondrial Function in Human Umbilical Vein Endothelial Cells

Methylglyoxal (MGO), an active metabolite of glucose, has been reported to induce vascular cell apoptosis in diabetic complication. Polydatin (PD), a small natural compound from Polygonum cuspidatum, has a number of biological functions, such as antioxidative, anti-inflammatory, and nephroprotective...

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Detalles Bibliográficos
Autores principales:	Pang, Ningbo, Chen, Tangting, Deng, Xin, Chen, Ni, Li, Rong, Ren, Meiping, Li, Yongjie, Luo, Mao, Hao, Haiyan, Wu, Jianbo, Wang, Liqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615983/ https://www.ncbi.nlm.nih.gov/pubmed/29057033 http://dx.doi.org/10.1155/2017/7180943

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