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The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages

BACKGROUND: The interaction of asbestos with macrophages drives two key processes that are linked to malignancy: (1) the generation of reactive oxygen species (ROS)/reactive nitrogen species (RNS) and (2) the activation of an inflammation cascade that drives acute and chronic inflammation, with the...

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Detalles Bibliográficos
Autores principales:	Pietrofesa, Ralph A., Woodruff, Patrick, Hwang, Wei-Ting, Patel, Priyal, Chatterjee, Shampa, Albelda, Steven M., Christofidou-Solomidou, Melpo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615985/ https://www.ncbi.nlm.nih.gov/pubmed/29075366 http://dx.doi.org/10.1155/2017/7395238

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