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The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases

Associations between epigenetic alterations and disease status have been identified for many diseases. However, there is no strong evidence that epigenetic alterations are directly causal for disease pathogenesis. In this study, we combined SNP and DNA methylation data with measurements of protein b...

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Detalles Bibliográficos
Autores principales: Ahsan, Muhammad, Ek, Weronica E., Rask-Andersen, Mathias, Karlsson, Torgny, Lind-Thomsen, Allan, Enroth, Stefan, Gyllensten, Ulf, Johansson, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617224/
https://www.ncbi.nlm.nih.gov/pubmed/28915241
http://dx.doi.org/10.1371/journal.pgen.1007005