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Downregulation of X-linked inhibitor of apoptosis protein by ‘7-Benzylidenenaltrexone maleate’ sensitizes pancreatic cancer cells to TRAIL-induced apoptosis
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential biological anticancer agent. However, a wide range of human primary cancers, including pancreatic cancer, display resistance to apoptosis induction by TRAIL. Therefore, this resistance needs to be overcome to allow TRAIL...
Autores principales: | Kim, So Young, Park, Sojung, Yoo, SeonA, Rho, Jin Kyung, Jun, Eun Sung, Chang, Suhwan, Kim, Kyung Kon, Kim, Song Cheol, Kim, Inki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617406/ https://www.ncbi.nlm.nih.gov/pubmed/28977846 http://dx.doi.org/10.18632/oncotarget.17841 |
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