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Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling

Previous study revealed that elevated expression of RAB27B in tissues is correlated with hepatocellular carcinoma (HCC) progression; however, the mechanisms involved in promoting HCC development are still unclear. Moreover, HCC tissues are not readily obtained during routine diagnosis. Therefore, to...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Ye, Xieqiong, Sun, Le, Gao, Fangyuan, Li, Yuxin, Ji, Xiaomin, Wang, Xuejiang, Feng, Ying, Wang, Xianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617411/
https://www.ncbi.nlm.nih.gov/pubmed/28977851
http://dx.doi.org/10.18632/oncotarget.18010