Cargando…

Gene polymorphisms in the PI3K/AKT/mTOR signaling pathway contribute to prostate cancer susceptibility in Chinese men

In this hospital-based case-control study of 413 prostate cancer (PCa) cases and 807 cancer-free controls, we investigated the role of functional single nucleotide polymorphisms (SNPs) of pivotal genes in the PI3K/AKT/mTOR pathway. We genotyped 17 SNPs in mTOR, Raptor, AKT1, AKT2, PTEN, and K-ras an...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ting, Gulinaer, Abulajiang, Shi, Xiaoli, Wang, Feng, An, Hengqing, Cui, Wenli, Li, Qiaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617424/
https://www.ncbi.nlm.nih.gov/pubmed/28977864
http://dx.doi.org/10.18632/oncotarget.18064