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Synergistic interaction between galectin-3 and carcinoembryonic antigen promotes colorectal cancer metastasis

In this study, we investigated the role of galectin-3 and carcinoembryonic antigen (CEA) in metastasis and survival of colorectal cancer (CRC) patients. CEA interacted with galectin-3 at the cell surface and cytoplasm of Caco2 and DLD1 CRC cells. Knocking down galectin-3 did not affect CEA expressio...

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Detalles Bibliográficos
Autores principales: Wu, Keng-Liang, Huang, Eng-Yen, Yeh, Wen-Ling, Hsiao, Chang-Chun, Kuo, Chung-Mou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617476/
https://www.ncbi.nlm.nih.gov/pubmed/28977916
http://dx.doi.org/10.18632/oncotarget.18721