Cargando…

Swine IRF3/IRF7 attenuates inflammatory responses through TLR4 signaling pathway

To explore the role of IRF3/IRF7 during inflammatory responses, we investigated the effects of swine IRF3/IRF7 on TLR4 signaling pathway and inflammatory factors expression in porcine kidney epithelial PK15 cell lines. We successfully constructed eukaryotic vectors PB-IRF3 and PB-IRF7, transfected t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Pei-Ge, Guan, Yan-Jing, Zha, Guang-Ming, Jiao, Xian-Qin, Zhu, He-Shui, Zhang, Cheng-Yu, Wang, Yue-Ying, Li, He-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617478/ https://www.ncbi.nlm.nih.gov/pubmed/28977918 http://dx.doi.org/10.18632/oncotarget.18740

Ejemplares similares

IRF3 and IRF7 mediate neovascularization via inflammatory cytokines
por: Simons, Karin H., et al.
Publicado: (2019)

DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulation
por: Andrilenas, Kellen K, et al.
Publicado: (2018)

Tagging Single Nucleotide Polymorphisms in the IRF1 and IRF8 Genes and Tuberculosis Susceptibility
por: Ding, Shiping, et al.
Publicado: (2012)

HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections
por: Sun, Lei, et al.
Publicado: (2017)

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
por: Lazear, Helen M., et al.
Publicado: (2013)

Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization
por: Dalskov, Louise, et al.
Publicado: (2020)

Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia
por: Ngwa, Conelius, et al.
Publicado: (2021)

Correction: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
por: Lazear, Helen M., et al.
Publicado: (2013)

TRIM14 expression is regulated by IRF‐1 and IRF‐2
por: Cui, Jingang, et al.
Publicado: (2019)

CD36 neutralisation blunts TLR2-IRF7 but not IRF3 pathway in neonatal mouse brain and immature human microglia following innate immune challenge
por: Gadagkar, Shruti Gururaj, et al.
Publicado: (2023)

TLR4 dependent heparan sulphate-induced pancreatic inflammatory response is IRF3-mediated
por: Akbarshahi, Hamid, et al.
Publicado: (2011)

Interferon Regulatory Factors IRF1 and IRF7 Directly Regulate Gene Expression in Bats in Response to Viral Infection
por: Irving, Aaron T., et al.
Publicado: (2020)

IRF7: role and regulation in immunity and autoimmunity
por: Ma, Wei, et al.
Publicado: (2023)

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses
por: Li, Qunfang, et al.
Publicado: (2011)

PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish
por: Zhao, Xin, et al.
Publicado: (2022)

IRF3 and IRF7 require SIRT1 for liquid–liquid phase separation and transactivation of IFN-1
Publicado: (2022)

TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9
por: Heinz, Leonhard X., et al.
Publicado: (2020)

Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding
por: De Ioannes, Pablo, et al.
Publicado: (2011)

Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
por: Cords, Leon, et al.
Publicado: (2023)

IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus
por: Manni, Michela, et al.
Publicado: (2015)

Grass Carp (Ctenopharyngodon idella) KAT8 Inhibits IFN 1 Response Through Acetylating IRF3/IRF7
por: Li, Meifeng, et al.
Publicado: (2022)

IRF7 Regulates TLR2-Mediated Activation of Splenic CD11c(hi) Dendritic Cells
por: Owens, Benjamin M. J., et al.
Publicado: (2012)

Up-Regulation of Intestinal Epithelial Cell Derived IL-7 Expression by Keratinocyte Growth Factor through STAT1/IRF-1, IRF-2 Pathway
por: Cai, Yu-Jiao, et al.
Publicado: (2013)

Classical Swine Fever Virus N(pro) Antagonizes IRF3 To Prevent Interferon-Independent TLR3- and RIG-I-Mediated Apoptosis
por: Hardy, Samuel, et al.
Publicado: (2021)

Evolution of the IRF Family in Salmonids
por: Clark, Thomas C., et al.
Publicado: (2021)

The Eukaryotic Translation Initiation Factor 4F Complex Restricts Rotavirus Infection via Regulating the Expression of IRF1 and IRF7
por: Chen, Sunrui, et al.
Publicado: (2019)

Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3
por: Zhang, Shen-Ying, et al.
Publicado: (2015)

Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development
por: Yamamoto, Michio, et al.
Publicado: (2011)

IRF1 Downregulation by Ras/MEK Is Independent of Translational Control of IRF1 mRNA
por: Komatsu, Yumiko, et al.
Publicado: (2016)

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
por: McDaniel, Margaret M., et al.
Publicado: (2020)

TRAF6 and IRF7 Control HIV Replication in Macrophages
por: Sirois, Mélissa, et al.
Publicado: (2011)

OR7-001 – By chip pyrin binds the IRF2 promoter
por: Wood, G, et al.
Publicado: (2013)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

Transcriptome Analysis of Microglia Reveals That the TLR2/IRF7 Signaling Axis Mediates Neuroinflammation After Subarachnoid Hemorrhage
por: Xu, Shenbin, et al.
Publicado: (2021)

IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo
por: Weiss, Miriam, et al.
Publicado: (2013)

Characterization and anti-inflammation role of swine IFITM3 gene
por: Li, He-Ping, et al.
Publicado: (2017)

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation
por: Langlais, David, et al.
Publicado: (2016)

Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
por: Campos Carrascosa, Lucia, et al.
Publicado: (2017)

Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses
por: Zhao, Min, et al.
Publicado: (2021)

IFNAR1 Is a Predictor for Overall Survival in Colorectal Cancer and Its mRNA Expression Correlated With IRF7 But Not TLR9
por: Chang, Liang-Che, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_t5mqfagrr5cbea71c08av7prdb