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Overexpression of miR-135b-5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and malignant neoplasm. The aberrant expression of miR-135b-5p and secreted frizzled-related protein 4 (SFRP4) has been revealed to be involved in various cancers. However, the clinical significance of miR-135b-5p and that of its potenti...

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Detalles Bibliográficos
Autores principales: Han, Xu, Saiyin, Hexige, Zhao, Junjie, Fang, Yuan, Rong, Yefei, Shi, Chenye, Lou, Wenhui, Kuang, Tiantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617497/
https://www.ncbi.nlm.nih.gov/pubmed/28977937
http://dx.doi.org/10.18632/oncotarget.19150