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Driving better and safer HER2-specific CARs for cancer therapy

Given the clinical efficacy of chimeric antigen receptor (CAR)-based therapy in hematological malignancies, CAR T-cell therapy for a number of solid tumors has been actively investigated. Human epidermal growth factor receptor 2 (HER2) is a well-established therapeutic target in breast, as well as o...

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Detalles Bibliográficos
Autores principales: Liu, Xianqiang, Zhang, Nan, Shi, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617544/
https://www.ncbi.nlm.nih.gov/pubmed/28977984
http://dx.doi.org/10.18632/oncotarget.17528