Cargando…

Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study

The adding-on phenomenon is a common complication in adolescent idiopathic scoliosis (AIS) patients after correction surgery. However, the risk factors of previous studies and the optimal treatment strategies remain controversial. The aim of this study was to identify new risk factors for the adding...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Wei, Chen, Chao, Li, Yifan, Yang, Changwei, Li, Ming, Li, Zhikun, Zhu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617722/
https://www.ncbi.nlm.nih.gov/pubmed/28930855
http://dx.doi.org/10.1097/MD.0000000000008099
_version_ 1783267042674081792
author Xu, Wei
Chen, Chao
Li, Yifan
Yang, Changwei
Li, Ming
Li, Zhikun
Zhu, Xiaodong
author_facet Xu, Wei
Chen, Chao
Li, Yifan
Yang, Changwei
Li, Ming
Li, Zhikun
Zhu, Xiaodong
author_sort Xu, Wei
collection PubMed
description The adding-on phenomenon is a common complication in adolescent idiopathic scoliosis (AIS) patients after correction surgery. However, the risk factors of previous studies and the optimal treatment strategies remain controversial. The aim of this study was to identify new risk factors for the adding-on phenomenon after posterior correction surgery in AIS patients and compare different treatment strategies to guide the selection of the lowest instrumented vertebra (LIV). All types of Lenke AIS patients who received correction surgery at our center from January 2009 to July 2014 were analyzed. The anteroposterior and lateral films were evaluated before surgery, at the 2-week follow-up, and at the 2-year or later follow-up. The patients were divided into 2 groups according to whether adding-on was observed at the last follow-up. The factors predictive of the adding-on phenomenon were identified in a multivariate binary logistic regression model. Different methods for LIV selection were compared in both the adding-on group and the control group (no adding-on). Out of the 346 patients reviewed, 92 met the inclusion criteria; 22 of these met the definition for distal adding-on, and were included in adding-on group. The remaining 70 patients were included in the no adding-on group. The average follow-up was 3.6 years. Touch classification (P < .000), Dnfs (P = .005), and vertebra number between LIV and angle velocity (AV) (P = .001) were significantly different between the 2 groups. Age, gender, Risser sign, and screw density were not found to be affiliated with the presence of adding-on. The results of the Scoliosis Research Society (SRS)-22 were not significantly different between the adding-on group and the control group for any section or overall (P > .05). Binary logistic regression results indicated that postoperative LAV deviation from the CSVL and Touch classification were independent predictive factors. Among the 4 methods, only choosing touch type A as LIV shows satisfactory outcome. The Touch classification is an important risk factor that is highly correlated with the incidence of the adding-on phenomenon. The best LIV choice to preserve the lumbar activity segment as much as possible is Touch type C, and no significant difference was observed in the SRS-22 scores between the Touch type C group and the control group in the short-term follow-up.
format Online
Article
Text
id pubmed-5617722
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-56177222017-10-13 Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study Xu, Wei Chen, Chao Li, Yifan Yang, Changwei Li, Ming Li, Zhikun Zhu, Xiaodong Medicine (Baltimore) 7100 The adding-on phenomenon is a common complication in adolescent idiopathic scoliosis (AIS) patients after correction surgery. However, the risk factors of previous studies and the optimal treatment strategies remain controversial. The aim of this study was to identify new risk factors for the adding-on phenomenon after posterior correction surgery in AIS patients and compare different treatment strategies to guide the selection of the lowest instrumented vertebra (LIV). All types of Lenke AIS patients who received correction surgery at our center from January 2009 to July 2014 were analyzed. The anteroposterior and lateral films were evaluated before surgery, at the 2-week follow-up, and at the 2-year or later follow-up. The patients were divided into 2 groups according to whether adding-on was observed at the last follow-up. The factors predictive of the adding-on phenomenon were identified in a multivariate binary logistic regression model. Different methods for LIV selection were compared in both the adding-on group and the control group (no adding-on). Out of the 346 patients reviewed, 92 met the inclusion criteria; 22 of these met the definition for distal adding-on, and were included in adding-on group. The remaining 70 patients were included in the no adding-on group. The average follow-up was 3.6 years. Touch classification (P < .000), Dnfs (P = .005), and vertebra number between LIV and angle velocity (AV) (P = .001) were significantly different between the 2 groups. Age, gender, Risser sign, and screw density were not found to be affiliated with the presence of adding-on. The results of the Scoliosis Research Society (SRS)-22 were not significantly different between the adding-on group and the control group for any section or overall (P > .05). Binary logistic regression results indicated that postoperative LAV deviation from the CSVL and Touch classification were independent predictive factors. Among the 4 methods, only choosing touch type A as LIV shows satisfactory outcome. The Touch classification is an important risk factor that is highly correlated with the incidence of the adding-on phenomenon. The best LIV choice to preserve the lumbar activity segment as much as possible is Touch type C, and no significant difference was observed in the SRS-22 scores between the Touch type C group and the control group in the short-term follow-up. Wolters Kluwer Health 2017-09-22 /pmc/articles/PMC5617722/ /pubmed/28930855 http://dx.doi.org/10.1097/MD.0000000000008099 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 7100
Xu, Wei
Chen, Chao
Li, Yifan
Yang, Changwei
Li, Ming
Li, Zhikun
Zhu, Xiaodong
Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study
title Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study
title_full Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study
title_fullStr Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study
title_full_unstemmed Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study
title_short Distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: A case–control study
title_sort distal adding-on phenomenon in adolescent idiopathic scoliosis patients with thoracolumbar vertebra fusion: a case–control study
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617722/
https://www.ncbi.nlm.nih.gov/pubmed/28930855
http://dx.doi.org/10.1097/MD.0000000000008099
work_keys_str_mv AT xuwei distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy
AT chenchao distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy
AT liyifan distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy
AT yangchangwei distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy
AT liming distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy
AT lizhikun distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy
AT zhuxiaodong distaladdingonphenomenoninadolescentidiopathicscoliosispatientswiththoracolumbarvertebrafusionacasecontrolstudy