Optimizing the fragment complementation of APEX2 for detection of specific protein-protein interactions in live cells

Dynamic protein-protein interactions (PPIs) play crucial roles in cell physiological processes. The protein-fragment complementation (PFC) assay has been developed as a powerful approach for the detection of PPIs, but its potential for identifying protein interacting regions is not optimized. Recent...

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Detalles Bibliográficos
Autores principales: Xue, Miaomiao, Hou, Junjie, Wang, Linlin, Cheng, Dongwan, Lu, Jingze, Zheng, Li, Xu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617831/
https://www.ncbi.nlm.nih.gov/pubmed/28955036
http://dx.doi.org/10.1038/s41598-017-12365-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617831/
https://www.ncbi.nlm.nih.gov/pubmed/28955036
http://dx.doi.org/10.1038/s41598-017-12365-9

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