Cargando…
Glibenclamide induces apoptosis by activating reactive oxygen species dependent JNK pathway in hepatocellular carcinoma cells
Glibenclamide (Gli) is a widely employed drug in the treatment of type 2 diabetes and many lines of evidence have described its anti-tumor effects in some neoplasms. The aim of the present study was to investigate the effect of Gli on apoptosis of human hepatocellular carcinoma (HCC) cells and to an...
Autores principales: | Yan, Bin, Peng, Zhiyong, Xing, Xiao, Du, Chunling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617909/ https://www.ncbi.nlm.nih.gov/pubmed/28801533 http://dx.doi.org/10.1042/BSR20170685 |
Ejemplares similares
-
Rasfonin promotes autophagy and apoptosis via upregulation of reactive oxygen species (ROS)/JNK pathway
por: Wang, Weijun, et al.
Publicado: (2016) -
Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway
por: Zhang, Lei, et al.
Publicado: (2017) -
Silibinin induces oral cancer cell apoptosis and reactive oxygen species generation by activating the JNK/c-Jun pathway
por: Zhang, Haibo, et al.
Publicado: (2023) -
Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation
por: Trejo-Solís, Cristina, et al.
Publicado: (2012) -
Ozone induces BEL7402 cell apoptosis by increasing reactive oxygen species production and activating JNK
por: Tang, Shuiying, et al.
Publicado: (2021)