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LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends
Processing of unintegrated linear HIV-1 cDNA by the host DNA repair system results in its degradation and/or circularization. As a consequence, deficient viral cDNA integration generally leads to an increase in the levels of HIV-1 cDNA circles containing one or two long terminal repeats (LTRs). Intr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618025/ https://www.ncbi.nlm.nih.gov/pubmed/28914817 http://dx.doi.org/10.3390/v9090259 |