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Optical Tracking and Digital Quantification of Beating Behavior in Bioengineered Human Cardiac Organoids

Organoid and organ-on-a-chip technologies are rapidly advancing towards deployment for drug and toxicology screening applications. Liver and cardiac toxicities account for the majority of drug candidate failures in human trials. Liver toxicity generally produces liver cell death, while cardiac toxic...

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Detalles Bibliográficos
Autores principales: Devarasetty, Mahesh, Forsythe, Steven, Shupe, Thomas D., Soker, Shay, Bishop, Colin E., Atala, Anthony, Skardal, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618030/
https://www.ncbi.nlm.nih.gov/pubmed/28644395
http://dx.doi.org/10.3390/bios7030024