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Optical Tracking and Digital Quantification of Beating Behavior in Bioengineered Human Cardiac Organoids
Organoid and organ-on-a-chip technologies are rapidly advancing towards deployment for drug and toxicology screening applications. Liver and cardiac toxicities account for the majority of drug candidate failures in human trials. Liver toxicity generally produces liver cell death, while cardiac toxic...
Autores principales: | Devarasetty, Mahesh, Forsythe, Steven, Shupe, Thomas D., Soker, Shay, Bishop, Colin E., Atala, Anthony, Skardal, Aleksander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618030/ https://www.ncbi.nlm.nih.gov/pubmed/28644395 http://dx.doi.org/10.3390/bios7030024 |
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