Cargando…
Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates hundreds of antioxidant genes, and is activated in response to oxidative stress. Given that many neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, H...
Autor principal: | Liddell, Jeffrey R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618093/ https://www.ncbi.nlm.nih.gov/pubmed/28820437 http://dx.doi.org/10.3390/antiox6030065 |
Ejemplares similares
-
Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
por: Liddell, Jeffrey R., et al.
Publicado: (2016) -
Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration
por: Abdalkader, Moataz, et al.
Publicado: (2018) -
Aging, NRF2, and TAU: A Perfect Match for Neurodegeneration?
por: Brackhan, Mirjam, et al.
Publicado: (2023) -
Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration
por: Colombo, Emanuela, et al.
Publicado: (2020) -
AGEs and neurodegeneration: the Nrf2/glyoxalase-1 interaction
por: Mastrocola, Raffaella
Publicado: (2016)