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Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing
Individualized medicine enables better diagnoses and treatment decisions for patients and promotes research in understanding the molecular underpinnings of disease. Linking individual patient’s genomic and molecular information with their clinical phenotypes is crucial to these efforts. To address t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618153/ https://www.ncbi.nlm.nih.gov/pubmed/28829408 http://dx.doi.org/10.3390/jpm7030007 |
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author | Horton, Iain Lin, Yaxiong Reed, Gay Wiepert, Mathieu Hart, Steven |
author_facet | Horton, Iain Lin, Yaxiong Reed, Gay Wiepert, Mathieu Hart, Steven |
author_sort | Horton, Iain |
collection | PubMed |
description | Individualized medicine enables better diagnoses and treatment decisions for patients and promotes research in understanding the molecular underpinnings of disease. Linking individual patient’s genomic and molecular information with their clinical phenotypes is crucial to these efforts. To address this need, the Center for Individualized Medicine at Mayo Clinic has implemented a genomic data warehouse and a workflow management system to bring data from institutional electronic health records and genomic sequencing data from both clinical and research bioinformatics sources into the warehouse. The system is the foundation for Mayo Clinic to build a suite of tools and interfaces to support various clinical and research use cases. The genomic data warehouse is positioned to play a key role in enhancing the research capabilities and advancing individualized patient care at Mayo Clinic. |
format | Online Article Text |
id | pubmed-5618153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-56181532017-09-29 Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing Horton, Iain Lin, Yaxiong Reed, Gay Wiepert, Mathieu Hart, Steven J Pers Med Review Individualized medicine enables better diagnoses and treatment decisions for patients and promotes research in understanding the molecular underpinnings of disease. Linking individual patient’s genomic and molecular information with their clinical phenotypes is crucial to these efforts. To address this need, the Center for Individualized Medicine at Mayo Clinic has implemented a genomic data warehouse and a workflow management system to bring data from institutional electronic health records and genomic sequencing data from both clinical and research bioinformatics sources into the warehouse. The system is the foundation for Mayo Clinic to build a suite of tools and interfaces to support various clinical and research use cases. The genomic data warehouse is positioned to play a key role in enhancing the research capabilities and advancing individualized patient care at Mayo Clinic. MDPI 2017-08-22 /pmc/articles/PMC5618153/ /pubmed/28829408 http://dx.doi.org/10.3390/jpm7030007 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Horton, Iain Lin, Yaxiong Reed, Gay Wiepert, Mathieu Hart, Steven Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing |
title | Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing |
title_full | Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing |
title_fullStr | Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing |
title_full_unstemmed | Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing |
title_short | Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing |
title_sort | empowering mayo clinic individualized medicine with genomic data warehousing |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618153/ https://www.ncbi.nlm.nih.gov/pubmed/28829408 http://dx.doi.org/10.3390/jpm7030007 |
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