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Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator

Saccharomyces cerevisiae cells are killed by zymocin, a tRNase ribotoxin complex from Kluyveromyces lactis, which cleaves anticodons and inhibits protein synthesis. Zymocin’s action requires specific chemical modification of uridine bases in the anticodon wobble position (U34) by the Elongator compl...

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Detalles Bibliográficos
Autores principales:	Mehlgarten, Constance, Prochaska, Heike, Hammermeister, Alexander, Abdel-Fattah, Wael, Wagner, Melanie, Krutyhołowa, Rościsław, Jun, Sang Eun, Kim, Gyung-Tae, Glatt, Sebastian, Breunig, Karin D., Stark, Michael J. R., Schaffrath, Raffael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618205/ https://www.ncbi.nlm.nih.gov/pubmed/28872616 http://dx.doi.org/10.3390/toxins9090272

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