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Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level
Accumulation of somatic mutations is critical for the transition of a normal cell to become cancerous. Mutations cause amino acid substitutions that change properties of proteins. However, it has not been studied as to what extent the composition and accordingly chemical properties of the cell prote...
Autores principales: | Tsuber, Viktoriia, Kadamov, Yunus, Brautigam, Lars, Warpman Berglund, Ulrika, Helleday, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618230/ https://www.ncbi.nlm.nih.gov/pubmed/28671612 http://dx.doi.org/10.3390/biom7030049 |
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