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Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level

Accumulation of somatic mutations is critical for the transition of a normal cell to become cancerous. Mutations cause amino acid substitutions that change properties of proteins. However, it has not been studied as to what extent the composition and accordingly chemical properties of the cell prote...

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Detalles Bibliográficos
Autores principales: Tsuber, Viktoriia, Kadamov, Yunus, Brautigam, Lars, Warpman Berglund, Ulrika, Helleday, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618230/
https://www.ncbi.nlm.nih.gov/pubmed/28671612
http://dx.doi.org/10.3390/biom7030049

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