Cargando…
tRNA Modification Detection Using Graphene Nanopores: A Simulation Study
There are over 100 enzyme-catalyzed modifications on transfer RNA (tRNA) molecules. The levels and identity of wobble uridine (U) modifications are affected by environmental conditions and diseased states, making wobble U detection a potential biomarker for exposures and pathological conditions. The...
Autores principales: | Onanuga, Khadijah, Begley, Thomas J., Chen, Alan A., Ranganathan, Srivathsan V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618246/ https://www.ncbi.nlm.nih.gov/pubmed/32962315 http://dx.doi.org/10.3390/biom7030065 |
Ejemplares similares
-
Capture, Unfolding, and Detection of Individual tRNA Molecules Using a Nanopore Device
por: Smith, Andrew M., et al.
Publicado: (2015) -
Nanopore-Based Detection of Viral RNA Modifications
por: Abebe, Jonathan S., et al.
Publicado: (2022) -
Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses
por: Chan, Cheryl, et al.
Publicado: (2018) -
Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNA(Lys3) Lacking ms(2)- (ms(2)t(6)A(37)) is Unable to Establish Sufficient Anticodon:Codon Interactions to Decode the Wobble Codon AAG
por: Narendran, Amithi, et al.
Publicado: (2021) -
RNA modifications detection by comparative Nanopore direct RNA sequencing
por: Leger, Adrien, et al.
Publicado: (2021)