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Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered via a Magnetic Nanocarrier
Here, we report the synthesis, characterization, and efficacy study of Fe/Fe(3)O(4)-nanoparticles that were co-labeled with a tumor-homing and membrane-disrupting oligopeptide and the iron-chelator Dp44mT, which belongs to the group of the thiosemicarbazones. Dp44mT and the peptide sequence PLFAERL(...
Autores principales: | Abayaweera, Gayani S., Wang, Hongwang, Shrestha, Tej B., Yu, Jing, Angle, Kyle, Thapa, Prem, Malalasekera, Aruni P., Maurmann, Leila, Troyer, Deryl L., Bossmann, Stefan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618274/ https://www.ncbi.nlm.nih.gov/pubmed/28672849 http://dx.doi.org/10.3390/jfb8030023 |
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