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Human MAP Tau Based Targeted Cytolytic Fusion Proteins
Some of the most promising small molecule toxins used to generate antibody drug conjugates (ADCs) include anti-mitotic agents (e.g., auristatin and its derivatives) which are designed to attack cancerous cells at their most vulnerable state during mitosis. We were interested in identifying a human c...
Autores principales: | Akinrinmade, Olusiji A., Jordaan, Sandra, Hristodorov, Dmitrij, Mladenov, Radoslav, Mungra, Neelakshi, Chetty, Shivan, Barth, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618294/ https://www.ncbi.nlm.nih.gov/pubmed/28653985 http://dx.doi.org/10.3390/biomedicines5030036 |
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