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Human MAP Tau Based Targeted Cytolytic Fusion Proteins

Some of the most promising small molecule toxins used to generate antibody drug conjugates (ADCs) include anti-mitotic agents (e.g., auristatin and its derivatives) which are designed to attack cancerous cells at their most vulnerable state during mitosis. We were interested in identifying a human c...

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Detalles Bibliográficos
Autores principales: Akinrinmade, Olusiji A., Jordaan, Sandra, Hristodorov, Dmitrij, Mladenov, Radoslav, Mungra, Neelakshi, Chetty, Shivan, Barth, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618294/
https://www.ncbi.nlm.nih.gov/pubmed/28653985
http://dx.doi.org/10.3390/biomedicines5030036

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