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CSPG4: A Target for Selective Delivery of Human Cytolytic Fusion Proteins and TRAIL

Chondroitin-sulfate proteoglycan 4 (CSPG4) is a transmembrane glycoprotein overexpressed on malignant cells in several cancer types with only limited expression on normal cells. CSPG4 is implicated in several signaling pathways believed to drive cancer progression, particularly proliferation, motili...

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Detalles Bibliográficos
Autores principales: Jordaan, Sandra, Chetty, Shivan, Mungra, Neelakshi, Koopmans, Iris, van Bommel, Peter E., Helfrich, Wijnand, Barth, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618295/
https://www.ncbi.nlm.nih.gov/pubmed/28657611
http://dx.doi.org/10.3390/biomedicines5030037

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