Comparison of Liver Detargeting Strategies for Systemic Therapy with Oncolytic Adenovirus Serotype 5

Oncolytic viruses would ideally be of use for systemic therapy to treat disseminated cancer. To do this safely, this may require multiple layers of cancer specificity. The pharmacology and specificity of oncolytic adenoviruses can be modified by (1) physical retargeting, (2) physical detargeting, (3...

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Detalles Bibliográficos
Autores principales: Nguyen, Tien V., Barry, Mary E., Turner, Mallory A., Crosby, Catherine M., Trujillo, Miguel A., Morris, John C., Barry, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618304/
https://www.ncbi.nlm.nih.gov/pubmed/28796161
http://dx.doi.org/10.3390/biomedicines5030046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618304/
https://www.ncbi.nlm.nih.gov/pubmed/28796161
http://dx.doi.org/10.3390/biomedicines5030046

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