Herpes Simplex Virus Type 1 Human Cervical Dorsal Root Ganglionitis

We present a case of a 34-year-old right-handed Caucasian male with chronic occipital neuralgia refractory to medical therapies and minimally invasive pain procedures who underwent surgical cervical dorsal root ganglionectomy which completely relieved his headaches. The histopathological and immunoh...

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Detalles Bibliográficos
Autores principales: Valyi-Nagy, Tibor, Rathore, Jaivir S., Rakic, Andrei M., Rathore, Ranvir S., Jain, Paavani, Slavin, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618399/
https://www.ncbi.nlm.nih.gov/pubmed/28966586
http://dx.doi.org/10.1159/000479146
Descripción
Sumario:We present a case of a 34-year-old right-handed Caucasian male with chronic occipital neuralgia refractory to medical therapies and minimally invasive pain procedures who underwent surgical cervical dorsal root ganglionectomy which completely relieved his headaches. The histopathological and immunohistochemical findings of the resected cervical dorsal root ganglia were consistent with active herpes simplex virus type 1 (HSV-1) infection causing ganglionitis. To the best of our knowledge, this case represents the first histopathologically proven HSV-1 cervical dorsal root ganglionitis in humans. This case provides an insight into a possible etiology of occipital neuralgia.

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