New Marine Antifouling Compounds from the Red Alga Laurencia sp.

Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight...

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Detalles Bibliográficos
Autores principales: Oguri, Yuko, Watanabe, Mami, Ishikawa, Takafumi, Kamada, Takashi, Vairappan, Charles S., Matsuura, Hiroshi, Kaneko, Kensuke, Ishii, Takahiro, Suzuki, Minoru, Yoshimura, Erina, Nogata, Yasuyuki, Okino, Tatsufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618406/
https://www.ncbi.nlm.nih.gov/pubmed/28846653
http://dx.doi.org/10.3390/md15090267
Descripción
Sumario:Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight previously known compounds isolated from the same samples. In particular, omaezol and hachijojimallene A showed potent activities (EC(50) = 0.15–0.23 µg/mL) against larvae of the barnacle Amphibalanus amphitrite.

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