New Marine Antifouling Compounds from the Red Alga Laurencia sp.

Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight...

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Autores principales: Oguri, Yuko, Watanabe, Mami, Ishikawa, Takafumi, Kamada, Takashi, Vairappan, Charles S., Matsuura, Hiroshi, Kaneko, Kensuke, Ishii, Takahiro, Suzuki, Minoru, Yoshimura, Erina, Nogata, Yasuyuki, Okino, Tatsufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618406/
https://www.ncbi.nlm.nih.gov/pubmed/28846653
http://dx.doi.org/10.3390/md15090267
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author Oguri, Yuko
Watanabe, Mami
Ishikawa, Takafumi
Kamada, Takashi
Vairappan, Charles S.
Matsuura, Hiroshi
Kaneko, Kensuke
Ishii, Takahiro
Suzuki, Minoru
Yoshimura, Erina
Nogata, Yasuyuki
Okino, Tatsufumi
author_facet Oguri, Yuko
Watanabe, Mami
Ishikawa, Takafumi
Kamada, Takashi
Vairappan, Charles S.
Matsuura, Hiroshi
Kaneko, Kensuke
Ishii, Takahiro
Suzuki, Minoru
Yoshimura, Erina
Nogata, Yasuyuki
Okino, Tatsufumi
author_sort Oguri, Yuko
collection PubMed
description Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight previously known compounds isolated from the same samples. In particular, omaezol and hachijojimallene A showed potent activities (EC(50) = 0.15–0.23 µg/mL) against larvae of the barnacle Amphibalanus amphitrite.
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spelling pubmed-56184062017-09-30 New Marine Antifouling Compounds from the Red Alga Laurencia sp. Oguri, Yuko Watanabe, Mami Ishikawa, Takafumi Kamada, Takashi Vairappan, Charles S. Matsuura, Hiroshi Kaneko, Kensuke Ishii, Takahiro Suzuki, Minoru Yoshimura, Erina Nogata, Yasuyuki Okino, Tatsufumi Mar Drugs Article Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight previously known compounds isolated from the same samples. In particular, omaezol and hachijojimallene A showed potent activities (EC(50) = 0.15–0.23 µg/mL) against larvae of the barnacle Amphibalanus amphitrite. MDPI 2017-08-28 /pmc/articles/PMC5618406/ /pubmed/28846653 http://dx.doi.org/10.3390/md15090267 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oguri, Yuko
Watanabe, Mami
Ishikawa, Takafumi
Kamada, Takashi
Vairappan, Charles S.
Matsuura, Hiroshi
Kaneko, Kensuke
Ishii, Takahiro
Suzuki, Minoru
Yoshimura, Erina
Nogata, Yasuyuki
Okino, Tatsufumi
New Marine Antifouling Compounds from the Red Alga Laurencia sp.
title New Marine Antifouling Compounds from the Red Alga Laurencia sp.
title_full New Marine Antifouling Compounds from the Red Alga Laurencia sp.
title_fullStr New Marine Antifouling Compounds from the Red Alga Laurencia sp.
title_full_unstemmed New Marine Antifouling Compounds from the Red Alga Laurencia sp.
title_short New Marine Antifouling Compounds from the Red Alga Laurencia sp.
title_sort new marine antifouling compounds from the red alga laurencia sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618406/
https://www.ncbi.nlm.nih.gov/pubmed/28846653
http://dx.doi.org/10.3390/md15090267
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