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SMAD2 Inactivation Inhibits CLDN6 Methylation to Suppress Migration and Invasion of Breast Cancer Cells

The downregulation of tight junction protein CLDN6 promotes breast cancer cell migration and invasion; however, the exact mechanism underlying CLDN6 downregulation remains unclear. CLDN6 silence is associated with DNA methyltransferase 1 (DNMT1) mediated DNA methylation, and DNMT1 is regulated by th...

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Detalles Bibliográficos
Autores principales:	Lu, Yan, Wang, Liping, Li, Hairi, Li, Yanru, Ruan, Yang, Lin, Dongjing, Yang, Minlan, Jin, Xiangshu, Guo, Yantong, Zhang, Xiaoli, Quan, Chengshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618512/ https://www.ncbi.nlm.nih.gov/pubmed/28867761 http://dx.doi.org/10.3390/ijms18091863

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