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“Dicing and Splicing” Sphingosine Kinase and Relevance to Cancer

Sphingosine kinase (SphK) is a lipid enzyme that maintains cellular lipid homeostasis. Two SphK isozymes, SphK1 and SphK2, are expressed from different chromosomes and several variant isoforms are expressed from each of the isozymes, allowing for the multi-faceted biological diversity of SphK activi...

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Detalles Bibliográficos
Autores principales: Haddadi, Nahal, Lin, Yiguang, Simpson, Ann M., Nassif, Najah T., McGowan, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618540/
https://www.ncbi.nlm.nih.gov/pubmed/28869494
http://dx.doi.org/10.3390/ijms18091891