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Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands

Tyrosine sulfation, a post-translational modification found on many chemokine receptors, typically increases receptor affinity for the chemokine ligand. A previous bioinformatics analysis suggested that a sulfotyrosine (sY)-binding site on the surface of the chemokine CXCL12 may be conserved through...

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Detalles Bibliográficos
Autores principales: Moussouras, Natasha A., Getschman, Anthony E., Lackner, Emily R., Veldkamp, Christopher T., Dwinell, Michael B., Volkman, Brian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618543/
https://www.ncbi.nlm.nih.gov/pubmed/28869519
http://dx.doi.org/10.3390/ijms18091894