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Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands
Tyrosine sulfation, a post-translational modification found on many chemokine receptors, typically increases receptor affinity for the chemokine ligand. A previous bioinformatics analysis suggested that a sulfotyrosine (sY)-binding site on the surface of the chemokine CXCL12 may be conserved through...
Autores principales: | Moussouras, Natasha A., Getschman, Anthony E., Lackner, Emily R., Veldkamp, Christopher T., Dwinell, Michael B., Volkman, Brian F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618543/ https://www.ncbi.nlm.nih.gov/pubmed/28869519 http://dx.doi.org/10.3390/ijms18091894 |
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