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Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium
Acetaldehyde is a highly reactive compound that causes various forms of damage to DNA, including DNA adducts, single- and/or double-strand breaks (DSBs), point mutations, sister chromatid exchanges (SCEs), and DNA–DNA cross-links. Among these, DNA adducts such as N(2)-ethylidene-2′-deoxyguanosine, N...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618592/ https://www.ncbi.nlm.nih.gov/pubmed/28891965 http://dx.doi.org/10.3390/ijms18091943 |