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Hsp90α Mediates BMI1 Expression in Breast Cancer Stem/Progenitor Cells through Facilitating Nuclear Translocation of c-Myc and EZH2

Heat shock protein 90 (Hsp90) is a molecular chaperone that facilitates the correct folding and functionality of its client protein. Numerous Hsp90-client proteins are involved in cancer development. Thus, Hsp90 inhibitors have potential applications as anti-cancer drugs. We previously discovered th...

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Detalles Bibliográficos
Autores principales:	Lee, Yueh-Chun, Chang, Wen-Wei, Chen, Yi-Ying, Tsai, Yu-Hung, Chou, Ying-Hsiang, Tseng, Hsien-Chun, Chen, Hsin-Lin, Wu, Chun-Chieh, Chang-Chien, Ju, Lee, Hsueh-Te, Yang, Huei-Fan, Wang, Bing-Yen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618635/ https://www.ncbi.nlm.nih.gov/pubmed/28914785 http://dx.doi.org/10.3390/ijms18091986

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