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Why Ubiquitin Has Not Evolved

Ubiquitin, discovered less than 50 years ago, tags thousands of diseased proteins for destruction. It is small (only 76 amino acids), and is found unchanged in mammals, birds, fish, and even worms, indicating that ubiquitin is perfect. Key features of its functionality are identified here using crit...

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Detalles Bibliográficos
Autores principales: Allan, Douglas C., Phillips, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618644/
https://www.ncbi.nlm.nih.gov/pubmed/28926941
http://dx.doi.org/10.3390/ijms18091995