Selective HDL-Raising Human Apo A-I Gene Therapy Counteracts Cardiac Hypertrophy, Reduces Myocardial Fibrosis, and Improves Cardiac Function in Mice with Chronic Pressure Overload

Epidemiological studies support an independent inverse association between high-density lipoprotein (HDL) cholesterol levels and heart failure incidence. The effect of selective HDL-raising adeno-associated viral serotype 8-human apolipoprotein (apo) A-I (AAV8-A-I) gene transfer on cardiac remodelin...

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Detalles Bibliográficos
Autores principales: Amin, Ruhul, Muthuramu, Ilayaraja, Aboumsallem, Joseph Pierre, Mishra, Mudit, Jacobs, Frank, De Geest, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618660/
https://www.ncbi.nlm.nih.gov/pubmed/28930153
http://dx.doi.org/10.3390/ijms18092012

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