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MG53 anchored by dysferlin to cell membrane reduces hepatocyte apoptosis which induced by ischaemia/reperfusion injury in vivo and in vitro

Hepatic ischaemia/reperfusion (HIR) induces severe damage on hepatocyte cell membrane, which leads to hepatocyte death and the subsequent HIR injury. In this study, we investigated the role and the mechanism of mitsugumin‐53 (MG53), a novel cell membrane repair protein, in protecting the liver again...

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Detalles Bibliográficos
Autores principales: Yao, Weifeng, Li, Haobo, Han, Xue, Chen, Chaojin, Zhang, Yihan, Tai, Wai Lydia, Xia, Zhengyuan, Hei, Ziqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618678/
https://www.ncbi.nlm.nih.gov/pubmed/28401647
http://dx.doi.org/10.1111/jcmm.13171