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MG53 anchored by dysferlin to cell membrane reduces hepatocyte apoptosis which induced by ischaemia/reperfusion injury in vivo and in vitro
Hepatic ischaemia/reperfusion (HIR) induces severe damage on hepatocyte cell membrane, which leads to hepatocyte death and the subsequent HIR injury. In this study, we investigated the role and the mechanism of mitsugumin‐53 (MG53), a novel cell membrane repair protein, in protecting the liver again...
Autores principales: | Yao, Weifeng, Li, Haobo, Han, Xue, Chen, Chaojin, Zhang, Yihan, Tai, Wai Lydia, Xia, Zhengyuan, Hei, Ziqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618678/ https://www.ncbi.nlm.nih.gov/pubmed/28401647 http://dx.doi.org/10.1111/jcmm.13171 |
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